European Chemical Biology Symposium
ECBS 2008
Barcelona, July 10-11, 2008
Scientific Committee Organising Committee Schedule Registration
What, When, Where:
The European Chemical Biology Symposium (ECBS) will be held in Barcelona, Spain, July 10th-11th, 2008, hosted by the two major Barcelona Science Parks: the Barcelona Science Park (PCB, Parc Científic de Barcelona) , and the Barcelona Biomedical Research Park (PRBB, Parc de Recerca Biomèdica de Barcelona).
Topics:
Current topics for the scientific program of ECBS include: Chemical tools for Biological Pathways, Chemico-Biological Databases, Systems Biology, European / US Chemical Biology Initiatives, Virtual and Experimental Screening, Protein-Protein Interactions, etc.
Goals:
The ECBS symposium aims to gather researchers from different scientific areas (chemistry, biology, pharmacology, cheminformatics, bioinformatics, etc.) interested in the interdisciplinary field of Chemical Biology, in order to learn and discuss with experts on the current and future research as well as the growing joint initiatives in this emerging field.
Info:
Further information, including a detailed scientific program and registration instructions will be available soon on this website.
Schedule:
Thursday, July 10 (Parc Científic Barcelona, PCB, http://www.pcb.ub.cat)
08:00 Registration
09:30 Official Sympsium Opening
10:00 ECBS Symposium Opening talk - Keynote address
New classes of Protein kinase inhibitors
Alexander Levitzki, The Hebrew University of Jerusalem, Israel
11:00 Coffee Break
Session 1: Protein-Protein Interactions
11:15 Protein-protein interaction inhibitors of transcription factors and kinases
Thorsten Berg, Max Planck Institute of Biochemistry, Martinsried, Germany
11:45 Targeting Protein-Protein Interactions in the Brain
Kristian Strømgaard, University of Copenhagen, Denmark
12:15 Protein-Protein Interactions in Apoptosis: the Smac-XIAP Example
Pierfausto Seneci, CISI and University of Milan, Italy
12:45 Polymerase Subunit Interaction Inhibitors as Antiviral Agents
Ulrich Kessler, PiKe Pharma GmbH, Zürich, Switzerland
13:00 Lunch
Session 2: Chemical Tools and Approaches to Investigate Biological Pathways / Targets (I)
15:00 Novel deorphanisation strategies based on academic screening
Marcel Hibert, Université Louis Pasteur de Strasbourg, France
15:30 Targeting Telomerase: Innovative approaches for bioactive compounds discovery in academia
Gerardo Turcatti, EPFL School of Life Sciences, Lausanne, Switzerland
16:00 Silver Bullet or Golden Hammer: Drug Target Specificity Profiling by Chemical Proteomics
Uwe Rix, CeMM - Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria
16:30 Coffee Break
Session 3: Chemical Tools and Approaches to Investigate Biological Pathways / Targets (II)
17:00 Chemical Tools for the validation of protein targets generated by dynamic ligation screening
Jörg Rademann, Leibniz-Institut für Molekulare Pharmakologie (FMP), Berlin, Germany
17:30 Bioprospecting in Cyanobacteria: Reverse Chemical Genetics Using Natural Products
Karl Gademann, Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland
18:00 Histone Acetylation and Methylation as Drug Discovery Targets
A. Ganesan, University of Southampton, United Kingdom
18:30 Chemistry driven drug discovery in the kinase inhibitor field
György Kéri, Semmelweis University and Vichem Chemie Research Ltd., Budapest, Hungary
21:00 ECBS 2008 Symposium Dinner
Friday, July 11 (Parc Recerca Biomedica Barcelona, PRBB, http://www.prbb.org)
Session 4: New Integrative Tools in Chemical Biology
09:00 Implementing Information Management in Academia
Damiano Banfi, Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland
09:30 Key Aspects for the Compilation of a Comprehensive Chemical Biology and Drug Discovery Screening Collection
Edgar Jacoby, Novartis Institute for Biomedical Research, Basel, Switzerland
10:00 Ligand Efficiency Indices for an Effective Mapping of the Chemico-Biological Space
Cele Abad-Zapatero, University of Illinois at Chicago, USA
10:30 Navigating through the Chemo-Target Space
Jordi Mestres, Grup Recerca Informàtica Biomèdica, Institut Municipal d’Investigacions Mèdiques (GRIB-IMIM), Barcelona, Spain
11:00 Coffee Break
Session 5: Chemical Biology in Europe
11:30 Introduction
Walter Rosenthal, Leibniz-Institut für Molekulare Pharmakologie (FMP), Berlin, Germany
11:40 Drug Discovery at Dundee
Stuart McElroy, Scottish Hit Discovery Facility, University of Dundee, Scotland
12:00 ChemBioNet: HTS on Academic Platforms
Jens Peter von Kries, Leibniz-Institut Für Molekulare Pharmakologie (FMP), Berlin, Germany
12:20 Scandinavian Chemical Biology Initiative
Kjetil Taskén, The Biotechnology Centre of Oslo, Norway
12:40 Chembiobank: Building an Annotated Molecular Library in Spain
Jordi Quintana, Parc Científic de Barcelona (PCB), Barcelona, Spain
13:00 ECBS Symposium Closing talk – Keynote address
Chemical Biology of the tumor suppressor p27kip
Ronald Frank, Helmholtz Centre for Infection Research, Braunschweig, Germany
13:45 Official ECBS Symposium Closing
14:15 Lunch
Scientific Committee:
| Jordi Quintana | PCB |
| Ferran Sanz | PRBB |
| Jordi Mestres | PRBB |
| Mabel Loza | USC |
| Fernando Albericio | PCB |
| Enrique Pérez-Payá | CIPF Valencia |
| Jens Peter von Kries | FMP Berlin |
| Jörg Rademann | FMP Berlin |
| Walter Rosenthal | FMP Berlin |
| Ronald Frank | HZI Braunschweig |
| Petr Bartunek | Prague |
| Chris Abell | Cambridge |
| Julie Frearson | Dundee |
| Gerardo Turcatti | EPFL Lausanne |
| Pierfausto Seneci | Milano |
| Kjetil Tasken | Oslo |
| Hugo Kubinyi | Heidelberg |
| James Wells | UC San Francisco |
| Robert Cooke | GlaxoSmithKline UK |
| Axel Ullrich | Max Planck Martinsried |
| Michael Freissmuth | Vienna |
| Thomas Mayer | Konstanz |
| Morten Meldal | Carlsberg |
Organizing Committee:
| Jordi Quintana | PCB Barcelona, Chair |
| Ferran Sanz | PRBB Barcelona |
| Mabel Loza | USC Santiago |
| Walter Rosenthal | FMP Berlin |
| Anne Hoener | FMP Berlin |
| Kjetil Tasken | Oslo |
| Pierfausto Seneci | Milano |
| Ronald Frank | HZI Braunschweig |

