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European Chemical Biology Symposium

ECBS 2008

Barcelona, July 10-11, 2008


Scientific Committee                                Organising Committee                                  Schedule                                Registration

What, When, Where:

The European Chemical Biology Symposium (ECBS) will be held in Barcelona, Spain, July 10th-11th, 2008, hosted by the two major Barcelona Science Parks: the Barcelona Science Park (PCB, Parc Científic de Barcelona) , and the Barcelona Biomedical Research Park (PRBB, Parc de Recerca Biomèdica de Barcelona).

Topics:

Current topics for the scientific program of ECBS include: Chemical tools for Biological Pathways, Chemico-Biological Databases, Systems Biology, European / US Chemical Biology Initiatives, Virtual and Experimental Screening, Protein-Protein Interactions, etc.

Goals:

The ECBS symposium aims to gather researchers from different scientific areas (chemistry, biology, pharmacology, cheminformatics, bioinformatics, etc.) interested in the interdisciplinary field of Chemical Biology, in order to learn and discuss with experts on the current and future research as well as the growing joint initiatives in this emerging field.

Info:

Further information, including a detailed scientific program and registration instructions will be available soon on this website.


Schedule:

Thursday, July 10 (Parc Científic Barcelona, PCB, http://www.pcb.ub.cat)

08:00   Registration

09:30   Official Sympsium Opening

10:00   ECBS Symposium Opening talk - Keynote address

New classes of Protein kinase inhibitors

Alexander Levitzki, The Hebrew University of Jerusalem, Israel

11:00   Coffee Break

Session 1:   Protein-Protein Interactions

11:15   Protein-protein interaction inhibitors of transcription factors and kinases

Thorsten Berg, Max Planck Institute of Biochemistry, Martinsried, Germany

11:45   Targeting Protein-Protein Interactions in the Brain

Kristian Strømgaard, University of Copenhagen, Denmark

12:15   Protein-Protein Interactions in Apoptosis: the Smac-XIAP Example

Pierfausto Seneci, CISI and University of Milan, Italy

12:45   Polymerase Subunit Interaction Inhibitors as Antiviral Agents

Ulrich Kessler, PiKe Pharma GmbH, Zürich, Switzerland

13:00   Lunch

Session 2:   Chemical Tools and Approaches to Investigate Biological Pathways / Targets (I)

15:00   Novel deorphanisation strategies based on academic screening

Marcel Hibert, Université Louis Pasteur de Strasbourg, France

15:30   Targeting Telomerase: Innovative approaches for bioactive compounds discovery in academia

Gerardo Turcatti, EPFL School of Life Sciences, Lausanne, Switzerland

16:00   Silver Bullet or Golden Hammer: Drug Target Specificity Profiling by Chemical Proteomics

Uwe Rix, CeMM - Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria

16:30   Coffee Break

Session 3:   Chemical Tools and Approaches to Investigate Biological Pathways / Targets (II)

17:00   Chemical Tools for the validation of protein targets generated by dynamic ligation screening

Jörg Rademann, Leibniz-Institut für Molekulare Pharmakologie (FMP), Berlin, Germany

17:30   Bioprospecting in Cyanobacteria: Reverse Chemical Genetics Using Natural Products

Karl Gademann, Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland

18:00   Histone Acetylation and Methylation as Drug Discovery Targets

A. Ganesan, University of Southampton, United Kingdom

18:30   Chemistry driven drug discovery in the kinase inhibitor field

György Kéri, Semmelweis University and Vichem Chemie Research Ltd., Budapest, Hungary

21:00   ECBS 2008 Symposium Dinner

 

Friday, July 11 (Parc Recerca Biomedica Barcelona, PRBB, http://www.prbb.org)

Session 4:   New Integrative Tools in Chemical Biology

09:00   Implementing Information Management in Academia

Damiano Banfi, Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland

09:30   Key Aspects for the Compilation of a Comprehensive Chemical Biology and Drug Discovery Screening Collection

Edgar Jacoby, Novartis Institute for Biomedical Research, Basel, Switzerland

10:00   Ligand Efficiency Indices for an Effective Mapping of the Chemico-Biological Space

Cele Abad-Zapatero, University of Illinois at Chicago, USA

10:30   Navigating through the Chemo-Target Space

Jordi Mestres, Grup Recerca Informàtica Biomèdica, Institut Municipal d’Investigacions Mèdiques (GRIB-IMIM), Barcelona, Spain

11:00 Coffee Break

Session 5:   Chemical Biology in Europe

11:30   Introduction

Walter Rosenthal, Leibniz-Institut für Molekulare Pharmakologie (FMP), Berlin, Germany

11:40   Drug Discovery at Dundee

Stuart McElroy, Scottish Hit Discovery Facility, University of Dundee, Scotland

12:00   ChemBioNet: HTS on Academic Platforms

Jens Peter von Kries, Leibniz-Institut Für Molekulare Pharmakologie (FMP), Berlin, Germany

12:20   Scandinavian Chemical Biology Initiative

Kjetil Taskén, The Biotechnology Centre of Oslo, Norway

12:40   Chembiobank: Building an Annotated Molecular Library in Spain

Jordi Quintana, Parc Científic de Barcelona (PCB), Barcelona, Spain

13:00   ECBS Symposium Closing talk – Keynote address

Chemical Biology of the tumor suppressor p27kip

Ronald Frank, Helmholtz Centre for Infection Research, Braunschweig, Germany

13:45   Official ECBS Symposium Closing

14:15   Lunch

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Scientific Committee:

Jordi Quintana PCB
Ferran Sanz PRBB
Jordi Mestres PRBB
Mabel Loza USC
Fernando Albericio PCB
Enrique Pérez-Payá CIPF Valencia
Jens Peter von Kries FMP Berlin
Jörg Rademann FMP Berlin
Walter Rosenthal FMP Berlin
Ronald Frank HZI Braunschweig
Petr Bartunek Prague
Chris Abell Cambridge
Julie Frearson Dundee
Gerardo Turcatti EPFL Lausanne
Pierfausto Seneci Milano
Kjetil Tasken Oslo
Hugo Kubinyi Heidelberg
James Wells UC San Francisco
Robert Cooke GlaxoSmithKline UK
Axel Ullrich Max Planck Martinsried
Michael Freissmuth Vienna
Thomas Mayer Konstanz
Morten Meldal Carlsberg

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Organizing Committee:

Jordi Quintana PCB Barcelona, Chair
Ferran Sanz PRBB Barcelona
Mabel Loza USC Santiago
Walter Rosenthal FMP Berlin
Anne Hoener FMP Berlin
Kjetil Tasken Oslo
Pierfausto Seneci Milano
Ronald Frank HZI Braunschweig

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